ABSTRACT
Forty one cases of dengue hemorrhagic fever, confirmed by viral isolation, accompanied by neurological signs compatible to the diagnosis of acute encephalopathy were observed in 3 University Hospitals in Jakarta during the period November 1975 to December 1977. Two of these children showed typical signs and symptoms of Reye's syndrome confirmed by liver biopsy.
Subject(s)
Adolescent , Child , Child, Preschool , Coma/complications , Dengue/complications , Humans , Indonesia , Infant , Nervous System Diseases/complications , Paresis/complications , Reye Syndrome/complications , Seizures/complications , Sleep StagesABSTRACT
Clinical studies in the treatment of 54 children suffering from DHF with a combination of dipyridamole and ASA as an adjuvant of our standard therapy consisted of fluid, electrolytes, blood, plasma and plasma expanders were evaluated. Heparin was administered in cases of DIC. It appeared that dipyridamole and ASA did not change the mortality significantly, but it prevented the progress of the severity of the disease from grade I and II to grade III and IV.